Research Interests
[1] Chemical Biology:
1a. Nucleic Acids Recognition & Therapeutics: Syntheses of new molecular entities for the targeting and stabilization of non-Watson-Crick nucleic acid structures, e.g., A-motif, C-motif, i-motif, G-Quadruplex DNA, hybrid G-quadruplex-duplex DNA & RNA.
Representative Publications: [1] A. Ali, M. Bansal and S. Bhattacharya, J. Phys. Chem. B (2015) 119, 5. [2] B. Maji, S. K. Samanta and S. Bhattacharya. Nanoscale (2014) 6, 3721. [3] B. Maji and S. Bhattacharya. Chem. Commun. (2014) 50, 6422. [4] A. Paul, B. Maji, S. K. Misra, A. K. Jain, K. Muniyappa and S. Bhattacharya. J. Med. Chem. (2012) 55, 7460. [5] A. K. Jain, V. Reddy, A. Paul, K. Muniyappa, and S. Bhattacharya. Biochemistry (2009) 48, 10693.
[1] Chemical Biology:
1b. Bioactive/ Gene Delivery & Knockdown: Plasmid DNA, siRNA, shRNA, aptamer delivery across eukaryotic cells; Cancer cell Targeting and Cancer Stem cells and in vivo study.
Representative Publications: [1] K. Kumar, B. Maiti, P. Kondaiah and S. Bhattacharya. Mol. Pharm. (2015) 12, 351. [2] S. K Misra, S. Naz, P. Kondaiah and S. Bhattacharya, Biomaterials (2014) 35, 1334. [3] P. Moitra, K. Kumar, P. Kondaiah and S. Bhattacharya, Angew. Chem. Int. Ed. (2014) 53, 1113 (2014). [4] S. K. Misra, J. Biswas, P. Kondaiah and S. Bhattacharya. PLoS ONE (2013) 8, e68305. [5] S. Bhattacharya and A. Bajaj, Chem. Commun. (2009) 4632 (Invited FEATURE article). [6] A. Bajaj, P. Kondaiah and S. Bhattacharya, J. Med. Chem. (2008) 51, 2533.
[2] Biological Membranes:
2a. Lipid Design, Synthetic Molecular Membranes & Membrane Biophysics: Structure-Function Studies; Vesicles, Micelles, Signalling in Self-organizing Aggregates; Lipid-DNA Complexation; Lipid-protein Interactions.
Representative Publications: [1] S. K. Misra, M. Muñoz-Ubeda, S. Datta, A.L. Barran-Berdon, C. Aicart-Ramos, P. Castro-Hartmann, P. Kondaiah, E. Junquera, S. Bhattacharya and E. Aicart, Biomacromol. (2013) 14, 3951. [2] M. Muñoz-Ubeda, S. Mishra, A. Barran-Berdon, C. Aicart, M. Sierra, J. Biswas, P. Kondaiah, E. Junquera, S. Bhattacharya, and E. Aicart. J. Am. Chem. Soc. (2011), 133, 18014. [3] J. Biswas, A. Bajaj and S. Bhattacharya, J. Phys. Chem. B (2011) 115, 478. [4] S. Bhattacharya and J. Biswas. Langmuir (2010) 26, 4642. [5] S. Bhattacharya and A. Bajaj. J. Phys. Chem. B (2007) 111, 13511.
[2] Surfactants in solution and complex fluids:
2b. De novo Design & Synthesis of New Surfactants: Bola amphiphiles, Gemini Surfactants, Ion-paired Amphiphiles, Metallo-surfactants, Multi-headed Surfactants; Monolayer films etc.
Representative Publications: [1] S. Datta, J. Biswas, and S. Bhattacharya, J. Colloid Interface Sci. (2014) 430, 85. [2] A. Pal, S. Datta, V. K. Aswal and S. Bhattacharya, J. Phys. Chem. B, (2012) 116, 13239. [3] S. Bhattacharya, and S. K. Samanta, J. Phys. Chem. Lett. (2011) 2, 914 [Invited PERSPECTIVES]. [4] S. Bhattacharya and J. Biswas. Langmuir (2011), 27, 1581 [5] S. Bhattacharya and N. Kumari, Coord. Chem. Rev. (2009) 253, 2133. (Invited Review). [6] S. Bhattacharya, K. Snehalatha, and V. Praveen Kumar, J. Org. Chem. (2003) 68, 2741. [7] J. Haldar, V.K. Aswal, P.S. Goyal and S. Bhattacharya, Angew. Chem. Int. Ed. (2001) 40, 1228.
[3] Supramolecular Chemistry:
Molecular Design of Soft Materials & Investigation using a variety of physical methods, e.g., rheology, probe-fluorescence, SANS, SAXS, XRD, DSC, AFM / SEM / TEM / CFM / POM etc.
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3a. Hydrogels: The evolution and design of new gelators & characterization of the resulting gels.
Representative Publications: [1] S. Bhattacharjee and S. Bhattacharya. Chem. Commun. (2015) 51 6765. [2] S. Bhattacharjee and S. Bhattacharya. Chem. Commun. (2014) 50, 11690. [3] S. K. Samanta and S. Bhattacharya. J. Mater. Chem. 2012, 22, 25277. [4] S. Bhattacharya and S. K. Samanta. Chem. Eur. J. 2012, 18, 16632. [5] A. Pal, H. Basit, S. Sen, V.K. Aswal and S. Bhattacharya, J. Mater. Chem., (2009) 19, 4325.
[3] Supramolecular Chemistry:
3b. Organogels: The evolution and design of new gelators & characterization of the resulting gels.
Representative Publications: [1] S. K. Samanta and S. Bhattacharya. Chem. Commun. (2013) 49, 1425. [2] S. Datta and S. Bhattacharya. Chem. Commun. (2012) 48, 877. [3] S. Datta, S. K. Samanta and S. Bhattacharya, Chem.- Eur. J. (2013) 19, 11364. [4] S. K. Samanta and S. Bhattacharya. Chem. Eur. J. (2012) 18, 15875. [5] S. Bhattacharya and S. K. Samanta, Langmuir (2009) 25, 8378 (Invited PERSPECTIVE article).
[3] Supramolecular Chemistry:
3c. Applications using Gels: Phase-selective gelation.
Representative Publications: [1] S. Bhattacharya and Y.K. Ghosh, Chem. Commun. 185 (2001) (Phase-selective Gelation’ term was coined for the first time). [2] S. Bhattacharya and A. Pal, J. Phys. Chem. B, 112, 4918 (2008 (Gelation of Binary Hydrocarbon Mixtures).
[3] Supramolecular Chemistry:
3d. Applications with Gels in Agriculture: Gels for sustained pheromone release toward live insect control in fruit orchard.
Representative Publications: [1] S. Bhattacharya, D. Bhagat, S. K. Samanta. Indian Patent Application #: 372/CHE/2014, January 2014. [2] D. Bhagat, S. K. Samanta & S. Bhattacharya. Scientific Reports, (2013) 3, 1294. [3] D. Bhagat, S. K. Samanta and S. Bhattacharya. Protocol Exchange, (2013), doi:10.1038/protex.2013.034.
[3] Supramolecular Chemistry:
3e. Molecular Probes: Sensors and probes for analytical & bio-analytical chemistry. Detection of biologically relevant species and environmentally hazardous ions and materials at nanogram level.
Representative Publications: [1] N. Kumari, S. Jha and S. Bhattacharya. Chem. Asian J. 2014, 9, 830. [2] N. Kumari, N. Dey and S. Bhattacharya. Analyst 2014, 139, 2370. [3] N. Dey, S. Samanta and S. Bhattacharya. ACS Appl. Mater. Interfaces 2013, 5, 8394. [4] N. Kumari, N. Dey, S. Jha and S. Bhattacharya. ACS Appl. Mater. Interfaces 2013, 5, 2438. [5] N. Kumari, S. Jha and S. Bhattacharya. J. Org. Chem. 2011, 76, 8215.
[4] Nanoscience & Technology:
4a. Nanocarbon-composites:
Representative Publications: [1] S. Bhattacharjee, S. K. Samanta, P. Moitra, K. Pramoda, Ram Kumar, S. Bhattacharya and C.N.R. Rao, Chem.- Eur. J. (2015) 21, 5467. [2] “Graphenes in Supramolecular Gels and in Biological Systems” S. Bhattacharya and S. K. Samanta, in “Graphene: Synthesis, Properties and Phenomena”, C.N.R. Rao & A K. Sood (Eds), Wiley-VCH, Weinheim, Germany (2013) pp. 339-372 [Invited Contribution]. [3] S. K. Samanta, K. S. Subrahmanyam, S. Bhattacharya and C.N.R. Rao, Chem.- Eur. J. (2012) 18, 2890. [4] S. K. Samanta, A. Gomathi, S. Bhattacharya and C.N.R. Rao Langmuir (2010) 26, 12230. [5] S. K. Samanta, A. Pal, S. Bhattacharya, and C.N.R. Rao. J. Mater. Chem. (2010), 20, 6881.
[4] Nanoscience & Technology:
4b. Metal Nanoparticle-composites:
Representative Publications: [1] S. Bhattacharya and J. Biswas, Nanoscale (2011) 3, 2924. [2] A. Pal, A. Srivastava and S. Bhattacharya, Chem. Eur. J. (2009) 15, 9169. [3] H. Basit, A. Pal, S. Sen, and S. Bhattacharya, Chem. Eur. J. (2008) 14, 6534. [4] S. Bhattacharya, A. Srivastava, A. Pal, Angew. Chem. Int. Ed. (2006) 45, 2934.
[4] Nanoscience & Technology:
4c. Nanobiotechnology:
Representative Publications: [1] B. Maji, S. K. Samanta and S. Bhattacharya. Nanoscale (2014), 6, 3721. [3] S. K. Misra, P. Moitra, B. S. Chhikara, P. Kondaiah and S. Bhattacharya, J. Mater. Chem. (2012) 22, 7985. [4] S. K. Misra, P. Kondaiah, S. Bhattacharya and C.N.R. Rao, Small (2012) 8, 131 [5] B. S. Chhikara, S. K. Misra and S. Bhattacharya. Nanotechnology, (2012), 23, 065101.
